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Multiple myeloma (MM) is a malignant plasma cell disease characterized by abnormal proliferation of bone marrow plasma cells accompanied by excessive production of monoclonal immunoglobulin or light chain (M protein). Keywords: Lenalidomide multiple myeloma (MM) allo-HSCT meta-analysis The overall survival (OS) of ≥2 years and progression-free survival (PFS) of ≥2 years of MM patients after allo-hematopoietic-stem-cell transplantation (HSCT) taking lenalidomide were analyzed, and the results were 64.9% (P=0.049) and 58.4% (P=0.890), respectively.ĭiscussion: Lenalidomide is effective in the treatment of MM patients after allo-HSCT, and reducing the incidence of infection and peripheral neuropathy, but it is not effective in reducing GVHD and blood system adverse reactions. Through meta-analysis of adverse reactions after taking lenalidomide, 35.3% (P=0.628) of participants developed acute graft-versus-host disease (GVHD) 22.6% (P=0.049) developed chronic GVHD 20.3% (P=0.001) developed infection 22.5% (P=0.352) had thrombocytopenia 32.5% (P<0.000) had neutropenia pain occurred in 17.8% (P=0.350) of patients, and peripheral neuropathy occurred in 17.8% (P=0.995) of participants. Through a single-arm meta-analysis of the disease status of MM patients after lenalidomide treatment, 3.6% of patients were in minimal response (MR, P=0.006), 39.0% were in complete remission (CR, P=0.169), 20.2% in partial remission (PR, P<0.001), 12.8% in very good partial remission (VGPR, P=0.049), and 9.7% in SD (P=0.023) the PD was 5.6% (P=0.010). Results: A total of 173 MM cases in 8 independent studies from 2007 to 2014 were included.
#STATA 14.0 SOFTWARE#
Statistical analysis was performed using the software STATA 14.0, and odds ratios (ORs) combined with 95% confidence intervals (CIs) were calculated to explore the efficacy and safety of lenalidomide in the treatment of MM patients after allogeneic cell transplantation. Methods: A systematic review and meta-analysis was conducted in English and Chinese databases, covering all available publications until 1 December 2020. This meta-analysis aimed to explore the effectiveness and safety of lenalidomide in the maintenance treatment of MM patients after allogeneic cell transplantation based on published data. Not in the traditional sense, but in the very traditional sense – classical music and music theory has always been a passion of mine and this has been a passion project for a long time now.Background: There has been long-standing controversy regarding the effectiveness and safety of lenalidomide as a maintenance treatment for patients with multiple myeloma (MM) after allogeneic cell transplantation. Why did we do this? I’m still asking myself that same question while introspectively reevaluating my life. How is that music generated? You write a string of notes that get converted to the midi file format. What is composer? It’s a way to create music.
#STATA 14.0 PROFESSIONAL#
but today, this post is for the slacker: from the undergraduate struggling through their Stata homework, to the professional who’s bored with the day-to-day grind, our new command composer is there to brighten up your day and aid with your ever evolving procrastination techniques. You’ve always been able to see your data, yet have you ever wanted to hear your data? “That’s absurd, I don’t need that.” There’s a big trend in today’s age involving visualizations, but truth be told, visualizations are so last season. Yo yo, what’s up my Stata-ites! DJ Control+D is in the house because today we’re talking about making music with Stata.
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